Unusual complication of intralesional corticosteroid in oral submucous fibrosis patient srikanth g 1, komal s 2, jyotsna r 1 and kalyana c. A wide range of treatment modalities have been tried ranging from medical, physical, or surgical interventions, but combinations of these have shown better results. The early form of the disease can be treated by medicinal means, however, advance stages needs surgical excision of the fibrotic tissue bands. We have mentioned all advanced treatments according to international standards slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. A wide range of treatment including drug management. Patients characteristically exhibit progressive reduction in mouth opening. These are injected into the fibrotic bands weekly for 68 weeks with regular monitoring of mouth opening. Management of oral submucous fibrosis with injection of. Oral submucous fibrosis osmf is an insidious chronic progressive disease of the oral cavity which is considered as a precancerous condition. Oral submucous fibrosis osf is a chronic condition almost exclusively occurring among indians and to a lesser extent in the other asiatic people. Management of oral submucous fibrosis by two different.
A wide range of treatment including drug therapy, surgical therapy, and physiotherapy have been attempted till date, with varying degrees of benefit, but none have been able to cure this disease. One such reaction of the collagen of oral mucosa to arecanut is oral submucous fibrosis. Oral submucous fibrosis osmf is a chronic debilitating and potentially malignant. Classification based on clinical features of osmf chandramani more et al 2011 m1 interincisal mouth opening up to or greater than 35 mm. Various local grafts have been used to cover the buccal mucosal defects after the fibrotic bands are released in oral submucous fibrosis. Use of diode lasers in treatment of oral submucous. Clinical evaluation of the role of tulsi and turmeric in. Osmf is the most poorly appreciated and inadequately managed disease. There was improvement in the symptoms of all the patients. Diode laser as a treatment for oral submucous fibrosis a case report figur e. The incidence of osmf still rising alarmingly and there is. Oral submucous fibrosis osmf is a persistent, progressive, precancerous condition of the oral mucosa, which is related with betel quid chewing habit.
Oral submucous fibrosis osmf, now labeled as a potentially malignant disorder, is rather unique in its clinical presentation. Scribd is the worlds largest social reading and publishing site. Different authors have suggested variety of treatment. The treatment aims at good release of fibrosis and to provide long term results in terms of mouth opening.
Stoppage of areca nut chewing is foremost important measure to treat osmf. Use of nasolabial flap in the management of oral submucous. Classification system for oral submucous fibrosis jiaomr and predominantly aimed at improving mouth movements. The suggested aetiological factor is the practice of certain customshabits of the inhabitants of south east asia. Review of drug treatment of oral submucous fibrosis. The pathogenesis is obscure, and till date, no definitive therapy is available for the management of osmf.
Index definition history keywords pathogenesis clinical features laboratory findings classification treatment 3. Complete details of surgery were explained to the patients and informed consent was obtained from each patient. Oral submucous fibrosis is a chronic disease characterised by progressive inability to open the mouth. Pdf an approach to management of oral submucous fibrosis. The treatment strategies sumit bhateja1, geetika arora2. The disease is rare in north america, and most cases seen in migrants from south east asia or india. Osmf is a chronic condition of the oral cavity which results in permanent disability.
Oral submucous fibrosisa new treatment regimen joms. Evaluation of efficacy of turmeric in management of oral. One new treatment modality which is gaining recognition is the use of turmeric in osmf. The aim of the present study was to compare the efficacy of spirulina and lycopene in the management of osmf. Effectiveness of pentoxifylline in the treatment of oral. Oral submucous fibrosis osmf is a potentially malignant disorder of the oral mucosa, mainly associated with the practice of chewing gutka and betel quid. A read is counted each time someone views a publication summary such as the title, abstract, and list of authors, clicks on a figure, or views or downloads the fulltext. The disease is rare in north america, and most cases seen in. Comparative efficacy of newer antioxidants spirulina and. As the disease progresses, the jaws become rigid to the point that the person is unable to open the mouth.
Role of collagen membrane in the treatment of advanced. Gupta s, jawanda mk, arora v, mehta n, yadav v, role of lycopene in preventing oral diseases as a nonsurgical aid of treatment, int j prev med, 6, 2015, 70. Pdf diode laser for treatment of osmf researchgate. Oral submucous fibrosis osmf is a highrisk premalignant condition predominantly seen in the indian subcontinent. Oral submucous fibrosis is a high risk precancerous lesion which predominantly affects indians, indians in diasporas, to a lesser extent in other asiatic, and sporadically in europeans. Oral submucous fibrosis and the role of curcumin in its treatment. Areca nut, betal quid, habits, oral sub mucous fibrosis, steroid therapy. This plays a role in the treatment of patients with oral submucous fibrosis because of its immunoregulatory effect. Various treatment modalities are available for its management, but these have largely been ineffective. This study was designed to determine the effect of pentoxifylline trental on the. Pdf oral submucous fibrosis osf is often mocked as a condition. Ifngamma, through its effect of altering collagen synthesis, appears to be a key factor to the treatment of patients with oral submucous fibrosis.
All patients were males and their ages ranged from 21 to. Curcumin is the principal curcuminoid and comprises approximately 25% of turmeric. Instruct patients regarding the importance of discontinuing the habit of chewing betel quid. Recent advancements in oral submucous fibrosis management. All the documented treatment modalities, ranging from medicinal treatment to surgical treatment are purely symptomatic in nature and total cure of the disease is still elusive. Oral submucous fibrosis is a premalignant condition commonly prevalent in india, pakistan, taiwan and sri lanka.
Several glucocorticoids are used for the treatment of osmf, short acting. The progression of disease is more rapid in younger age group. Capsaicin, an active principle, mild irritant, which brings about epithelial and connective tissue changes in osmf patients. Oral submucous fibrosis osmf, a precancerous condition of the oral cavity, has been studied by a number of workers in the field.
Management of oral submucous fibrosis by two different drug. The disease has a high malignant potential and thus should be diagnosed and treated at the earliest. Medical and surgical treatment options for oral submucous. Oral submucous fibrosis is a chronic insidious disease which was previously designated as a premalignant condition but presently categorized under potentially malignant disorders who 2005. All the available treatment modalities give only symptomatic relief which are of short duration.
Total of 30 patients with clinically diagnosed osmf patients. R crri,saveetha dental college and hospitals, chennai abstract. Latest treatmet modality of osmf is lasers, the hyaline bands are excised with the help of lasers which is a very good alternative to traditional surgical therapy but a bit costly and most of the osmf patients who have come to. The study aimed to evaluate the efficacy of spirulina along with different physiotherapeutic modalities in the management of osmf. Oral submucous fibrosis is defined as an insidious chronic disease affecting any part of the oral cavity and sometimes the pharynx. Management of oral submucous fibrosis by different. Research article assessment of utility of tulsi and. Pdf non surgical approaches in treatment of osf researchgate. Oral submucous fibrosis an overview sciencedirect topics.
Oral submucous fibrosis is a chronic, complex, premalignant 1% transformation risk condition of the oral cavity, characterized by juxtaepithelial inflammatory reaction and progressive fibrosis of the submucosal tissues the lamina propria and deeper connective tissues. Know all about the disease, including its possible causes, symptoms, diagnosis and treatment options. An approach to management of oral submucous fibrosis. Laser treatment video for oral submucous fibrosis part. The treatment of oral submucous fibrosis is a challenging task for a clinician. Surgical fibrolysis and skin grafts in the management of. Oral submucous fibrosis osmf is a potentially malignant disease that results in progressive juxtaepithelial fibrosis of the oral soft tissues. Betel nut and pan are freely available in the united kingdom, and in a city such as leicester, one might expect to find 3000 cases of oral submucosal fibrosis. The oral submucous fibrosis osmf as defined by pindborg and sirsat as an insidious chronic fibrotic disease that involves the oral mucosa and occasionally the pharynx and upper third of oesophagus.
The available epidemiological data showed a clearcut geographical and ethnic predisposition, which suggested that certain customshabits prevalent among the population groups in southeast asia might be possible etiological factors. Oral submucous fibrosisa case report medcrave online. M2 interincisal mouth opening between 25 and 35 mm m3 interincisal mouth opening between 15 and 25 mm m4 interincisal mouth opening less than 15 mm. Successful treatment of oral submucous fibrosis with local injections of chymotrypsin, hyaluronidase, and dexamethasone is reported. Treatment options for oral submucous fibrosis iosr journal.
Successful use of inferiorly based nasolabial flaps in the management of oral submucous. Aloe vera in the treatment for oral submucous fibrosis a. Pentoxifylline, a methylxanthine derivative, has vasodilating properties and is believed to increase the vascularity of the mucosal layer. Oral submucous fibrosis causes, symptoms, treatment and.
A total of 25 patients consented for surgical treatment. Sixtyeight subjects with clinicopathologically diagnosed osmf were included in. Joshi subsequently coined the termed oral submucous fibrosis osf for the condition in 1953. The study concludes that aloe vera can be an alternative, safe, and effective treatment regime in the management of oral submucous fibrosis. Most treatment modalities in osmf have centered on relief of the burning sensation and release of the fibrotic bands to improve mouth opening. Patient education and counseling is one of the foremost important step in the management of osmf which includes. Oral submucous fibrosis osmf is a potentially malignant disorder largely seen in the southasian countries where areca nut is found to be the main predisposing factor. Oral submucous fibrosis osmf is a chronic disorder seen only in persons who chew betel areca catechu nuts, pan masala or gutkha and is characterized by tightening of the buccal, and sometimes palatal and lingual mucosae, causing trismus. Advanced treatment of oral submucous fibrosis by dr. Elastic degradation of collagen and ultrastructurally, partial or complete degeneration of collagen into elastin. Unusual complication of intralesional corticosteroid in.
Oral submucous fibrosis osmf is a chronic disease of insidious onset and a prevailing potentially malignant disorder characterized by juxtaepithelial inflammatory reaction along with mucosal fibrosis. As the disease progresses, the oral mucosa becomes stiff due to the formation of fibrotic bands in the cheek, ultimately leading to. The awareness of such a condition among oral physicians can help in timely diagnosis and thus appropriate treatment can be administered depending on the degree of involvement. Several classifications based on clinical and histological features, have been put forth by various researchers, based on different aspects of osmf. The pathogenesis is poorly understood and the disease is difficult to treat. However, with the increase in immigration of people from the indian subcontinent, dental professionals in many developed countries will encounter this disease in the near future. Osmf is associated with immunological changes altered levels of serum immunoglobulins and the effect of treatment especially antioxidants and levamisole on serum ig is not known. Definition it is an insidious chronic disease affecting any part of the oral cavity and sometimes the pharynx. Natural ayurvedic treatment of osmf along with life style modification can help in lowering the symptoms of osmf and may help in curing the disease. The principal actions of drug therapy include antifibrotic, anti. Oral submucous fibrosis and the role of curcumin in its. Oral submucous fibrosis osf is a precancerous condition of the oral mucosa. Patients with osmf need treatment for trismus correction, reconstructive surgery for. Pdf aloe vera in the management of oral submucous fibrosis.
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